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Retro 2

CAS No. 1201652-50-7

Retro 2 ( 2-{[(5-methyl-2-thienyl)methylene]amino} )

Catalog No. M23372 CAS No. 1201652-50-7

Retro 2 is a plant toxin ricin ?inhibitor, itprotects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Retro 2
  • Note
    Research use only, not for human use.
  • Brief Description
    Retro 2 is a plant toxin ricin ?inhibitor, itprotects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface.
  • Description
    Retro 2 is a plant toxin ricin ?inhibitor, itprotects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface.
  • Synonyms
    2-{[(5-methyl-2-thienyl)methylene]amino}
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    toxin ricin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1201652-50-7
  • Formula Weight
    320.4
  • Molecular Formula
    C19H16N2OS
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    CC1=CC=C(S1)C=NC2=CC=CC=C2C(=O)NC3=CC=CC=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Morgens D W , Chan C , Kane A J , et al. Retro-2 protects cells from ricin toxicity by inhibiting ASNA1-mediated ER targeting and insertion of tail-anchored proteins[J]. eLife Sciences, 2019, 8.
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